2021 NDC/HCPCS Crosswalk


The NDC/HCPCS crosswalk provides a listing of each National Drug Code that is assigned to a HCPCS. The crosswalk is updated monthly, but contains all prior updates, along with providing details on what changes occurred that month.

For NDC/HCPCS crosswalk questions or file layout, view our NDC Crosswalk Questions and Answers.

April 2021

NDC to HCPCS Crosswalk (Excel, 1019 KB)
NDC to HCPCS Crosswalk (PDF, 1036 KB)
Date Changes (PDF, 55 KB)
Coding Changes (PDF, 53 KB)
Conversion Factor Changes (PDF, 56 KB)
Records and NDCs Added (PDF, 59 KB)
Records and NDCs Removed (PDF, 57 KB)
Additional Changes (PDF, 54 KB)

March 2021

NDC to HCPCS Crosswalk (Excel, 1014 KB)
NDC to HCPCS Crosswalk (PDF, 1032 KB)
Date Changes (PDF, 55 KB)
Coding Changes (PDF, 53 KB)
Conversion Factor Changes (PDF, 56 KB)
Records and NDCs Added (PDF, 60 KB)
Records and NDCs Removed (PDF, 56 KB)
Additional Changes (PDF, 54 KB)

February 2021

NDC to HCPCS Crosswalk (Excel, 1043 KB)
NDC to HCPCS Crosswalk (PDF, 1203 KB)
Date Changes (PDF, 54 KB)
Coding Changes (PDF, 52 KB)
Conversion Factor Changes (PDF, 55 KB)
Records and NDCs Added (PDF, 59 KB)
Records and NDCs Removed (PDF, 66 KB)
Additional Changes (PDF, 53 KB)

January 2021

NDC to HCPCS Crosswalk (Excel, 1082 KB)
NDC to HCPCS Crosswalk (PDF, 6090 KB)
Date Changes (PDF, 177 KB)
Coding Changes (PDF, 173 KB)
Conversion Factor Changes (PDF, 178 KB)
Records and NDCs Added (PDF, 181 KB)
Records and NDCs Removed (PDF, 205 KB)
Additional Changes (PDF, 175 KB)



Last Updated: 04/02/2021